Who is the Colorado Criminal Justice Reform Coalition?

Our mission is to reverse the trend of mass incarceration in Colorado. We are a coalition of nearly 7,000 individual members and over 100 faith and community organizations who have united to stop perpetual prison expansion in Colorado through policy and sentence reform.

Our chief areas of interest include drug policy reform, women in prison, racial injustice, the impact of incarceration on children and families, the problems associated with re-entry and stopping the practice of using private prisons in our state.

If you would like to be involved please go to our website and become a member.


Tuesday, September 16, 2008

Potential New Drug Fights Overdose And Addiction

ScienceDaily (Sep. 15, 2008) — Chemists are reporting development of what they term the most powerful substance ever discovered for eliminating cocaine from the body, an advance that could lead to the world's first effective medicine for fighting overdoses and addictions of the illicit drug.

Their findings are scheduled for the Sept. 24 issue of the Journal of the American Chemical Society, a weekly publication.

In the new study, Chang-Guo Zhan and colleagues point out no effective anti-cocaine medication currently exists for cocaine abuse. One of the most promising approaches focuses on substances that mimic butyrylcholinesterase (BChE), a natural blood protein that helps break down and inactivate the drug, researchers say. However, natural BChE is too weak and ineffective for medical use, the researchers note.

The researchers describe design and produce the most potent, stable BChE structure ever produced. In lab studies, that form of BChE broke down, or metabolized, cocaine 2,000 times faster than the body's natural version of BChE, the scientists say, noting that reducing levels of the drug in the blood is a key to fighting overdose in humans. The substance also prevented convulsions and death when injected into mice that were given overdoses of cocaine, they note.


Science Daily